A blood test measuring metanephrines assesses the levels of these metabolites of adrenaline and noradrenaline. These metabolites are typically present in low concentrations in the blood. Elevated levels may indicate the presence of a tumor called a pheochromocytoma or paraganglioma, which can overproduce these hormones. A 24-hour urine collection can also provide this diagnostic information. Comparing results from both blood and urine tests provides a more comprehensive assessment.
Determining the concentration of these metabolites provides crucial information for diagnosing and managing these rare tumors. Early diagnosis is essential as these tumors, while often benign, can cause significant cardiovascular problems, including dangerously high blood pressure. The development of this diagnostic test significantly improved the ability to detect these conditions, often before the onset of severe symptoms. Timely detection and treatment are critical for preventing potentially life-threatening complications.